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Improved
(IVT Reaction) Productivity

OUR CURRENT EFFORTS

We aspire to enable biopharma companies to exceed their goals in developing and delivering life-transforming nucleic-acid therapies, through production and GMP manufacturing of biopharmaceutical drug substances.

Global academic and industry collaborations are supporting sapientis in establishing a premier ecosystem to enable scientific progress and shared learning to speed up the availability of biotechnological solutions. Application include infectious diseases, immunotherapies against cancer, and precision medicine in rare diseases. Pilot projects will deliver products for clinical trial activities.

sapientis is planning to start operating the state-of-the-art cGMP biotechnological pilot plant including development laboratories as from Q4 2023 to provide comprehensive GMP development and the complete spectrum of services from discovery to drug substance and drug product development and manufacturing for New Biological Entities (NBEs) worldwide.

WHY PARTNERING WITH SAPIENTIS

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mRNA PLATFORM

SOLUTION

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SINGLE USE BIOREACTORS: EFFICIENCY AND OPERATIONAL FLEXIBILTY

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FROM CLINICAL DEVELOPMENT TO COMMERCIAL MANUFACTURING

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FLEXIBLE PURIFICATION PROCESS W/ IMPROVED PRODUCTIVITY

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FILL AND FINISH FOR R&D AND FOR THE COMMERCIAL USE

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COST SAVINGS IN PRODUCTION PROCESS AND SKILLED LABOUR

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OUR CAPABILITIES

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AI / ML ENABLED
DRUG DISCOVERY

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ANIMAL VALIDATION MODELS

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INVARIANT
VACCINES

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PERSONALIZED
VACCINES

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INFECTIOUS
DISEASES

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PANDEMIC RESPONSE COMMON FLU

OUR SERVICES IN mRNA MANUFACTURING

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1. PLASMID
MANUFACTURING

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4. LNP
FORMULATION (THROUGH OUR PARTNERS)

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2. MRNA
PRODUCTION

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5. STERILE
FILTRATION

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3. PURIFICATION AND CONCENTRATION

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6. FINAL FILL/
QA RELEASE

(R&D/SMALL VOLUME)

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